MDAiRE™ Skincare Products

MDAiRE™ Skincare Products

MDAiRE™ Skincare Products

MDAiRE Triple Threat Trio: Neck Tyte-R 50 ml, RXR Retinol Anti-Aging Serum 30 ml, Regenerative ECM Eye Complex 15 ml, standing in a row by height on frosted stone and powder snow, a white bauble and frosted pine beside them.

Triple Threat Trio

Dermatologist-formulated treatments for the eyes, neck, and décolleté. Engineered to drive cellular renewal, target puffiness, smooth, and correct the skin. Regenerative ECM Eye Complex is a powerful eye...

$319.60$418.00Save $98.40 Extra 15% off during the Holiday Preview
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MDAiRE Daily Skincare Bundle: Vitamin C-FK Brightening Complex 30 ml, NMF Hydrator Barrier Repair 50 ml, RXR Retinol Anti-Aging Serum 30 ml, Regenerative ECM Eye Complex 15 ml, standing in a row on frosted stone and powder snow, white and pale-blue baubles and frosted pine behind them.

Daily Skincare Bundle

The original line up of our active treatments. Targets brightening and antioxidant defense, cellular renewal, barrier reinforcement, and eye rejuvenation. Innovative active ingredients with advanced delivery systems to...

$425.43$589.00Save $163.57 Extra 15% off during the Holiday Preview
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Get Started Bundle with MDAiRE Bio Cleanse 5.5 Face Wash, NMF Hydrator Mini, and Peptide Lip Mask in gallery 1

Get Started Bundle

Deeply purify and prepare your skin,  strengthen the skin barrier with long-lasting hydration, and support your lips for a smoother, more supple pout. The perfect introduction to our...

$98.60$132.00Save $33.40 Extra 15% off during the Holiday Preview
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MDAiRE Skincare Essentials Bundle: Regenerative ECM Eye Complex 15 ml, Vitamin C-FK Brightening Complex 30 ml, NMF Hydrator Barrier Repair 50 ml, Neck Tyte-R 50 ml, RXR Retinol Anti-Aging Serum 30 ml, standing in a row on frosted stone and powder snow, white and pale-blue baubles and frosted pine behind them.

Skincare Essentials Bundle

A system built to deliver real, visible results from your face to your décolleté. Target brightening, barrier repair, cellular renewal, eye rejuvenation, and neck firming in one dedicated...

$525.30$727.00Save $201.70 Extra 15% off during the Holiday Preview
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MDAiRE Complete System Bundle: Vitamin C-FK Brightening Complex 30 ml, Bio-Cleanse 5.5 Face Wash 200 ml, RXR Retinol Anti-Aging Serum 30 ml, NMF Hydrator Barrier Repair 50 ml, Regenerative ECM Eye Complex 15 ml, Neck Tyte-R 50 ml, standing in a staggered group on frosted stone and powder snow, white and pale-blue baubles and frosted pine behind them.

Complete System Bundle

Total-system protection and correction at the cellular level. Strengthen your barrier, defend against environmental damage, renew cell turnover, prevent and target the visible signs of aging on your...

$560.15$775.00Save $214.85 Extra 15% off during the Holiday Preview
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Glow on the Go Bundle with MDAiRE mini skincare products and bright blue cosmetic bag in gallery position 1

Glow on the Go Bundle

Your skincare routine in mini sizes that go wherever you do. Four of our most essential active treatments in convenient travel-sized bottles, packaged in the oversized MDAiRE cosmetic...

$233.75$324.00Save $90.25 Extra 15% off during the Holiday Preview
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Luxe Sample Pack

Luxe Sample Pack

The perfect introduction to your new skincare routine. Featuring three of our best-selling hero products in convenient 8ml sizes, this kit allows you to experience the transformative power...

$112.20$132.00 15% off during the Holiday Preview
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Not sure where to start?

Let Dr. Kappel build your routine

Take the 1-minute skincare quiz and get a personalized product recommendation.

MDAiRE™ is the official skincare line created by Dr. Stefani Kappel, a board-certified, double fellowship-trained dermatologist with over 15 years of experience treating and studying skin. Every product in this collection is formulated with clinical-grade active ingredients and advanced delivery systems designed to promote skin health at the cellular level.

Our dermatologist-developed skincare collection includes everything you need to cleanse, hydrate, and repair your skin barrier. From our bestselling NMF Hydrator Barrier Repair cream and Vitamin C-FK Brightening Complex to our RXR Retinol Anti-Aging Serum and Regenerative ECM Eye Complex, each product is built around the science of barrier health, the foundation of healthy, resilient skin.

Whether you're looking for anti-aging skincare, brightening serums, skin barrier repair, gentle cleansers for sensitive skin, mineral sunscreen, or targeted treatments for fine lines, wrinkles, dark circles, melasma, hyperpigmentation, acne, or uneven skin tone and texture, this collection has you covered. MDAiRE products feature proven ingredients like hyaluronic acid, peptide complexes, ceramides, retinol, vitamin C, and beta glucan, all working together to strengthen, protect, and renew your skin.

Every MDAiRE™ product is cruelty free, paraben free, fragrance free, and phthalate free. Rated 4.9 out of 5 stars with over 1,000 reviews, our skincare is trusted by thousands who believe in science-backed, results-driven routines. Shop individual products or explore our curated skincare bundles, including build-your-own options, and save even more with Subscribe & Save. Not sure where to start? Take our Skincare Quiz for a personalized routine recommendation.